Various lifestyle and environmental factors to identify if they might increase the risk of RA.
From a previous work one of the cohort of this project, we identified passive smoking in childhood as being associated with an increased risk of RA, in future active smokers.
Analyses form this project provided interesting results on the following factors:
1. The findings showed that transit disturbance, such as chronic diarrhoea, might also increase this risk.
2. Hormonal factors were studied and early menopause was identified as being associated with an increased risk of RA in women, whereas a high lifetime exposure to oestrogen seems to decrease this risk.
3. Also it was found that dietary factors such as adherence to Mediterranean diet (rich in vegetables, olive oils and omega 3) might protect for developing RA in non-smokers.
This project continues with new research focus.