Baseline characteristics were available for 1,145 patients. Those with r-axSpA were more likely to be male, were older, and had longer disease duration.
Follow-up ASDAS at 1 year was available in 290 patients. Two thirds of the patients achieved ASDAS low disease state at one year regardless of radiographic status (nr-axSpA: 64.2% vs r-axSpA: 66.1, Diff: -1.9%, 95% CI -13.7 to 9.8). Further, no significant differences were seen between the groups in attaining ASDAS CII (nr-axSpA: 50.7% vs r-axSpA: 44.7%, Diff: 6.0%, 95% CI -7.8 to 19.8%) or MI (nr-axSpA: 20% vs r-axSpA: 18.7%, Diff: 1.3%, 95% CI -9.7 to 12.3%).
Although there appeared to be some differences in the baseline characteristics when exploring this cohort, according to radiographic status, which are likely related to the natural history of the disease; the level of biologic response was comparable between the groups supporting the concept of axSpA as a single disease entity.