Effect of T-cell exhaustion profiles of synovial fluid and peripheral blood from JIA patients on disease pathogenesis and prognosis

Objectives of the Project

The project will enlighten the role of exhausted T cells on the pathogenesis of JIA. The T cell co-inhibitory receptors, which are extensively expressed by exhausted T cells, play a vital role in aiding the immune systems reaction towards an antigen, including in the defining of the self and non-self.
We will try to find the role of exhausted T cells and T cell co-inhibitory receptors for predicting the outcome of JIA and try to find a novel therapeutic target molecule.

Facts and Figures

Project lead
MD MSc E Sag
Hacettepe University
FOREUM research grant: €100.00
2018 - 2021

Meet the team

MD MSc E Sag
Hacettepe University
Prof. S Ozen
Hacettepe University
Prof. B Deleuran
Aarhus University