Preclinical phases of RMDs

There is a high interest in defining the earliest stages of Rheumatic and Musculoskeletal Diseases (RMDs). Early recognition of the initial phases of RMDs is important for scientists, clinicians and patients for gaining a better insight into the pathogenesis of these diseases and facilitating the development of timely interventions or even preventive approaches. In the last years it is increasingly recognized that characteristic molecular and cellular processes antedate the clinical phases of individual RMDs.

FOREUM initiated a call for research proposals and received 20 letters of intent. Five applications were invited to submit a full proposal and three are funded.

Novel treatment targets in early-stage OA
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ENVI-RA
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Development of new tools for prediction and prevention of RA (PREDICT-RA)
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A prediction score for individuals at risk for SLE by integrating clinical, serologic and transcriptomic data
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