The clinical presentation of early arthritis (EA) is variable and patients may evolve differently over time. Some will develop RA or PsA, while others may remain with mild symptoms or even become symptom free. Management of EA has been the main focus of rheumatology research. The treatment model ‘the-earlier-the-better’ has dramatically benefited patients mostly by reducing disease burden and avoiding joint damage. However, this model may have led to ‘overdiagnosis’ and ‘overtreatment’.
The project team proposes to evaluate EA using an approach that excludes the, likely biased, rheumatologist’s opinion, by analyzing data from three independet EA cohorts and applying analytical techniques. As a result different latent forms o EA and their evolvement over time shall be presented.